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![]() Your Ad Here DeSoto County, Florida DeSoto County is a county located in the U.S. state of Florida. The U.S. Census Bureau 2005 estimate for the county is 35,406. Its county seat is Arcadia. History De Soto County was created in 1887. It was named for Hernando de Soto, Spanish explorer, whose name was also honored in Hernando County.
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